M methaqualone was not adjusted appreciably with the introduction of neither the Q242W nor the T237I mutation within the α In see from the reasonably higher functional potencies of etomidate, loreclezole, and methaqualone as GABAAR modulators, all 3 modulators are envisioned to bind towards the receptor in the small-Power conformation. https://lukasbhmoo.blogdigy.com/top-guidelines-of-methaqualone-drug-classification-44115916