The reverse transcriptase also has ribonuclease exercise that degrades the viral RNA in the course of the synthesis of cDNA, as well as DNA-dependent DNA polymerase activity that makes a sense DNA through the antisense cDNA.[sixty nine] With each other, the cDNA and its complement form a double-stranded viral DNA https://hivhub.in/hiv-epidemic-in-india-trends-and-state-wise-distribution/